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14.06.2018 kl 15:23 483

https://www.fiercebiotech.com/biotech/targovax-tumbles-after-chemotherapy-cocktail-data-dent-pancreatic-cancer-plans

"Targovax is still deciding the next steps for TG01 and the wider TG program. Management sees a future for the anti-RAS neoantigen platform and a phase 1 trial of follow-up asset TG02 in colorectal cancer is continuing toward a 2019 readout.

The future for TG01 is less clear. Targovax will spend the next few months talking to its clinical advisers with a view to presenting a revised TG development plan in the fall.

The silver lining of the enforced strategic rethink is that Targovax has freed up money for its ONCOS oncolytic adenovirus program. As Targovax noted in its release, oncolytic viruses are back in fashion, with Johnson & Johnson and Merck both striking recent deals to add such drugs to their armories.

Targovax has taken its oncolytic virus, ONCOS-102, as far as a phase 2 mesothelioma trial. Armed with resources originally allocated to TG01, Targovax is looking into expanding the mesothelioma trial."
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